Quality Assurance

Pharmaceutical Quality System (PQS) Questions 1. The manufacture of sterile products requires: A. Minimal controlsB. Specific controls and measuresC. Only visual inspectionD. No specialized systemsAnswer: B Questions 2. The primary goal of the PQS for sterile products is to: A. Increase production speedB. Minimize microbial, particulate, and endotoxin/pyrogen contaminationC. Reduce documentationD. Eliminate the need for … Read more

Questions and answers of Incident Procedure in Pharma EUGMP- Annex-1 Question 1. What is an incident as per the definition? A planned deviation B. An unplanned or uncontrolled event C. A customer complaint D. A routine process step Answer: B Question 2. Incidents occur due to: A. Market complaints B. System failure, equipment breakdown, or manual … Read more

Single-Use Systems (SUS) & Closed systems EUGMP- Annex-1 Questions 1. Single-use systems (SUS) are used as an alternative to: A. Terminal sterilizationB. Reusable equipmentC. Gowning systemsD. HVAC systemsAnswer: B Questions 2. SUS may consist of: A. Only filtersB. Only sensorsC. Individual components or multiple componentsD. Stainless-steel tanksAnswer: C Questions 3. SUS should be designed to … Read more

Environmental and Process Monitoring EUGMP- Annex-1 Questions 1. The purpose of an environmental monitoring programme is to ensure: A. Faster batch releaseB. That cleanrooms maintain appropriate air cleanlinessC. Operator competencyD. Media sterilityAnswer: B Questions 2. Environmental monitoring programmes must also: A. Increase product shelf lifeB. Detect excursions from environmental limitsC. Eliminate all viable particlesD. Replace … Read more

Environmental Monitoring – Total Particle Monitoring EUGMP- Annex-1 Questions 1. A total particle monitoring program should be established to: A. Reduce batch sizesB. Assess contamination risks and maintain sterile environmentsC. Replace viable monitoringD. Evaluate operator performanceAnswer: B Questions 2. Environmental monitoring limits for Grade D in operation are: A. Fixed by regulationB. Not predeterminedC. Same … Read more

Aseptic process simulation (APS)/ media fill questions EUGMP- Annex-1 Questions 1. What is another name for an Aseptic Process Simulation (APS)? A. Sterility testB. Media fillC. Endotoxin challengeD. Cleaning validationAnswer: B Questions 2. What is the purpose of periodic APS? A. To replace routine monitoringB. To verify the effectiveness of controls for aseptic processingC. To … Read more

Multiple-Choice Questions (MCQs) & answer on cleaning validation Considering Packaging Materials & Tubing and Hoses Questions 1: Which of the following is a primary consideration before using tubing or hoses in pharmaceutical manufacturing? A. Color of the tubing B. Biocompatibility and inertness with the contact material C. Cost of the tubing D. Manufacturer’s brand name Answer: … Read more

Multiple-Choice Questions (MCQs) & answer on cleaning validation Objective-Type Questionnaire 1.Question :  According to the 1993 U.S. FDA cleaning validation guidance, cleaning validation is not required when the cleaning process is used:A. Between batches of different products on multipurpose equipmentB. Only between batches of the same productC. Between batches of high-potency pharmaceuticalsD. For any dedicated … Read more

Questions and Answers on Validation Master Plan (VMP) Questions 1. The VMP should be: A. Very detailed and lengthyB. Brief, concise, and clearC. A replacement for all SOPsD. Written only by external auditorsAnswer: B Questions 2. The VMP should not repeat information already documented elsewhere; instead, it should: A. Omit referencesB. Refer to existing documents … Read more