- OBJECTIVE
- To lay down the procedure for Operation of Tap density apparatus, Make Electro lab.
- SCOPE
- This SOP shall provide the Operating procedure of Tap density apparatus of quality control department.
- RESPONSIBILITY
- Officer/ Executive – Quality Control
- ACCOUNTABILITY
- Head QC/QA
- PROCEDURE
- Before starting the operation Check for the area cleanliness and instrument cleanliness.
- Connect the pin to power supply.
- Switch on the power.
- The instrument displays Main Menu.
- Choose the mode menu either ‘USP or User’ by pressing Digit scroll key.
- Press the method key to set USP 1 or USP II.
- CONDITION I (If as per USP 1):
- Stroke Height : 14mm ± 2 mm.
- Strokes / Min : Nominal 300 times.
- Tap count 1 : 500 times.
- Tap count 2 : 750 times.
- Tap count 3 : 1250 times.
- Press set key, to set tap count 1 to 500 by using ⇑⇓⇐ key
- Press enter key, set tap count 2 to 750 by using ⇑⇓⇐ key
- Press enter key, set tap count 3 to 1250 by using ⇑⇓⇐ key
- Press enter key, set clock timely using ⇑⇓⇐ key
- Press enter key, set date by using shift key and ⇑⇓ key
- Press enter key, it will ask for “Print last result “if you need shift cursor to Y other wise to N. Press enter key.
- Press reset key, Now your method get saved as per USP 1.
- Press start key, input weight of sample by using shift key and⇑⇓ key in grams.
- Press enter key, input initial volume (Vo) by using shift key and⇑⇓ key key in ml.
- Keep the cylinder in Holder and press start key; it will give a taps box 500 times.
- Measured tapped volume (Va) and input by using shift key and ⇑⇓ key
- Press enter key and press start key. It will give a taps force 750 times.
- Measured tapped volume (Vb) input by using shift key and ⇑⇓ key
- Note: If the difference volume of 1st tap and 2nd tap i.e. Va – Vb is more than 2% then proceed for tap count 3 i.e. 1250 times by same manner. Measure the final volume (Vf) if so not the stop the experiment in Tap count 2 only.
- Give the connection to printer and go to printing mode by using SET and Enter Key.
- Set printing mode to Y, automatically printing will come. We can get tap density Initial Density, compressibility Index and Hausner Ratio.
- CONDITION II (if as per USP II):
- Stroke height : 3mm+/-10 %.
- Strokes/min : about 250 times.
- Tap count 1 : 500 times.
- Tap count 2 : 750 times.
- Tap count 3 : 1250 times.
- Proceed same as condition 1 for step 5.8 – 5.22.
- CONDITION III (if as per user mode):
- The mode to user mode by using set keys and shift key.
- Press set key, set taps count as per the product specification.
- Press start key to start the tapping.
- Measured the volume and calculate manually.
- Calculate the bulk density of the blend according to the formula given below.
- Bulk density g/cc = Wt. of the sample : Volume of the cylinder
- If in between tapping need stop use (STOP KEY).
- Press reset key.
- Enter the details in the instrument log book.
- Switch off the instrument.
- Forms and Records (Annexures)
- Not Applicable
- Distribution
- Master copy – Quality Assurance
- Controlled copies- Quality Assurance, Production, Quality Control.engineering
- History
Date Revision Number Reason for Revision – 00 New SOP
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