QUESTIONS & ANSWERS

Environmental Monitoring – Total Particle Monitoring EUGMP- Annex-1

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Environmental Monitoring – Total Particle Monitoring EUGMP- Annex-1 Questions 1. A total particle monitoring program should be established to: A. Reduce batch sizesB. Assess contamination risks and maintain sterile environmentsC. Replace viable monitoringD. Evaluate operator performanceAnswer: B Questions 2. Environmental monitoring limits for Grade D in operation are: A. Fixed by regulationB. Not predeterminedC. Same … Read more

Environmental and personnel monitoring – viable particle EUGMP- Annex-1

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Environmental and personnel monitoring – viable particle EUGMP- Annex-1 Questions 1. Microbial monitoring in aseptic operations should be: A. RareB. Performed only weeklyC. FrequentD. OptionalAnswer: C Questions 2. A combination of methods for microbial monitoring may include: A. Chemical analysisB. Settle plates, air sampling, glove, gown, surface samplingC. Weight measurementsD. Only visual inspectionAnswer: B Questions … Read more

Aseptic process simulation (APS)/ media fill questions EUGMP- Annex-1

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Aseptic process simulation (APS)/ media fill questions EUGMP- Annex-1 Questions 1. What is another name for an Aseptic Process Simulation (APS)? A. Sterility testB. Media fillC. Endotoxin challengeD. Cleaning validationAnswer: B Questions 2. What is the purpose of periodic APS? A. To replace routine monitoringB. To verify the effectiveness of controls for aseptic processingC. To … Read more

Questions and Answers on Quality Control (QC)

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Questions and Answers on Quality Control (QC) Questions 1. QC personnel supporting sterile manufacturing activities must have training and experience in: A. Marketing and financeB. Microbiology, sterility assurance, and process knowledgeC. Mechanical engineering onlyD. Warehouse operationsAnswer: B Questions 2. Specifications for raw materials, components, and products should include limits for: A. Moisture onlyB. Microbial, particulate, … Read more

Multiple-Choice Questions (MCQs) & Answers on cleaning validation Considering Packaging Materials & Tubing and Hoses

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Multiple-Choice Questions (MCQs) & answer on cleaning validation Considering Packaging Materials & Tubing and Hoses Questions 1: Which of the following is a primary consideration before using tubing or hoses in pharmaceutical manufacturing? A. Color of the tubing B. Biocompatibility and inertness with the contact material C. Cost of the tubing D. Manufacturer’s brand name Answer: … Read more

Multiple-Choice Questions (MCQs) & answer on cleaning validation

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Multiple-Choice Questions (MCQs) & answer on cleaning validation Objective-Type Questionnaire 1.Question :  According to the 1993 U.S. FDA cleaning validation guidance, cleaning validation is not required when the cleaning process is used:A. Between batches of different products on multipurpose equipmentB. Only between batches of the same productC. Between batches of high-potency pharmaceuticalsD. For any dedicated … Read more

Questions and Answers on Validation Master Plan (VMP)

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Questions and Answers on Validation Master Plan (VMP) Questions 1. The VMP should be: A. Very detailed and lengthyB. Brief, concise, and clearC. A replacement for all SOPsD. Written only by external auditorsAnswer: B Questions 2. The VMP should not repeat information already documented elsewhere; instead, it should: A. Omit referencesB. Refer to existing documents … Read more