Handling of Spillage of Materials

Handling of Spillage of Materials

Procedure

Spillage of any material shall be handled immediately when observed and effectively as per the procedure mentioned below  :

  • The personnel working in the concerned department shall immediately inform the Incharge of the concerned department about the spillage of material.
  • The concerned department Incharge shall inform QA about the complete details of spilled materials.
  • The personnel who shall handle the spillage wear proper protective dress such as aprons, hand gloves, masks,s and safety glasses to prevent the material is volatile or irritating to the nose and eyes.
  • If the material is a solid one, then the same shall be collected with the help of a plastic scoop and a soft broom into a container for disposal as waste. In case of very fine powder being spread over a large area of the floor, then the floor may be cleaned with a vacuum cleaner. The floor shall be thoroughly cleaned first with a wet mop and then dried with a dry mop.
  • If the material is a liquid one, the same shall be collected, with the help of a plastic scoop and a sponge, into a container for disposal as waste. The floor shall be cleaned first with a wet mop and then dried with a dry mop.
  • If the material is sticky or greasy, the same shall be collected with the help of a plastic scoop and soft broom, into a container for disposal as waste. Thoroughly clean the floor first with a mop dipped in hot water and then dry it with a dry mop.
  • If the spilled material is corrosive one (acidic or alkali) the same shall be neutralized with acid or alkali, as the case may be, before collecting with the help of a plastic scoop and soft broom into a container for disposal as waste. Thoroughly clean the floor first with wet mop and then dry with a dry mop.
  • If the spilled material is a controlled substance, then the spilled material shall be collected in a polythene bag, which shall be closed tightly with a thread/rubber band and the same shall be weighed and labeled as under :

Spillage of Materials

 

  • Name of the material
  • Batch No.
  • Name of the Manufacturer
  • date and Exp. Date
  • Weight of Material

This polythene bag containing spilled material shall be kept near the container from which it has fallen off for inspection by QA. The details regarding spilled material shall be entered in the “Spilled Material Logbook” .

Spilled material shall neither be used in the manufacturing/testing of products nor shall it be disposed of as a waste material without the permission of QA. After getting the approval of QA, the material shall be disposed of as per SOP “Disposal and Destruction of Material” and details of disposing of materials shall be recorded in the respective Logbook.

Concerned department personnel must get proper training for handling of spillage of Material.

About Abha Maurya

Ms. Abha Maurya is the Author and founder of pharmaceutical guidance, he is a pharmaceutical Professional from India having more than 18 years of rich experience in pharmaceutical field. During his career, he work in quality assurance department with multinational company’s i.e Zydus Cadila Ltd, Unichem Laboratories Ltd, Indoco remedies Ltd, Panacea Biotec Ltd, Nectar life Science Ltd. During his experience, he face may regulatory Audit i.e. USFDA, MHRA, ANVISA, MCC, TGA, EU –GMP, WHO –Geneva, ISO 9001-2008 and many ROW Regularities Audit i.e.Uganda,Kenya, Tanzania, Zimbabwe. He is currently leading a regulatory pharmaceutical company as a head Quality. You can join him by Email, Facebook, Google+, Twitter and YouTube

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